RESEARCH AND AUDIT

RESEARCH AND AUDIT

Research is a valued part of the departmental activities. Several research and audit projects are currently being undertaken in the department of Neurosurgery at Frenchay Hospital. These include laboratory-based scientific studies, clinical research into neurosurgical disorders, clinical trials, and audit projects which are aimed at improving the standards of patient care in our unit.

There are two principle research units within our department: the Neurosurgery Research Group and the Spinal Research and Development Unit.

  • Neurosurgery Research Group

    The particular interests of the group include head injury, subarachnoid haemorrhage, trigeminal neuralgia, acoustic neuromas, pituitary tumours and functional stereotactic surgery for Parkinson's disease and movement disorders.

  • Spinal Research and Development Unit

    In collaboration with Medtronic Sofamor-Danek this group is involved with the investigation of spinal instrumentation in the treatment of degenerative spinal disorders, image guidance in spinal surgery, and the outcome of surgery for cervical spondylosis.

Major Areas of Basic Scientific Research

  1. The Endogenous Molecular Neurotrophin and Trk Receptor response to traumatic brain injury. Mr Nitin Patel, Dr P Sharples

  2. The neurotrophin and glucocorticoid responses to traumatic brain injury in relation to outcome. Mr P Grundy, Dr P Sharples, Prof S Lightman

  3. The biomechanics of the cervical spine. Crispin Wigfield, Richard Nelson (Department of Anatomy, University of Bristol)

Major Areas of Clinical Research

  1. The surgical treatment of Parkinson's Disease - Subthalamic Nucleotomy & Growth factor treatment in human Parkinson's disease. Mr Nik Patel, Mr S Gill

  2. Application of image guidance to the surgical treatment of spinal disorders. Mr C Wigfield, Mr C Bolger.

  3. The use of an artificial cervical joint in the treatment of cervical spondylosis. Mr S Gill, Mr R Nelson, Prof. J T Robertson, Mr C Wigfield.

  4. Interbody fusion devices in the surgical treatment of cervical spondylosis. Mr C Wigfield, Prof. J T Robertson, Mr R Nelson.

  5. Prospective outcome of single level anterior cervical decompression and fusion for the treatment of cervical spondylosis. Mr C Wigfield,Prof J T Robertson, Mr R Nelson.

  6. Conservative Management of Lumbar Disc Prolapse Mr K Greenfield, Mr R Nelson

  7. Ocular Micro-Tremor in comatose patients. Miss S Bojanic, Mr C Bolger

  8. ISAT Trial for intracranial aneurysmal haemorrhage

  9. International Study of Unruptured Intracranial Aneurysm (ISUIA) Trial

CLINICAL AUDIT

  1. Audit of the process and documentation of informed consent Mr R Nelson, Clinical Standards Committee, Department of Neurosurgery

  2. Functional hearing preservation following acoustic neuroma surgery Prof H Coakham, Mr R Edwards

  3. Outcome of Acoustic Neuroma surgery Prof H Coakham, Mr R Nelson, Y Clarke.

  4. Audit of Microvascular Decompression for Trigeminal Neuralgia, Acoustic Neuroma & Endoscopic Surgery Professor H Coakham, Y Clarke

    Ongoing database of patients treated since 1991. Range of patient follow-up 1-19 years (mean 6.25 years).

  5. Audit of use of Magnetic Resonance Angiography (MRA) in diagnosing neurovascular compression in patients with trigeminal neuralgia. Prof. H Coakham, Dr S Renowden, Yvonne Clarke

  6. Outcome of surgical excision of AVMs of the trigeminal nerve root entry zone causing trigeminal neuralgia Mr.R Nelson, Prof H Coakham, Dr S Renowden

  7. Diagnosis and surgical management and Outcome of Arachnoid Webs causing trigeminal neuralgia, and outcome following surgery Prof. H Coakham, Dr S Renowden

    n= 5, completion Feb 2001

  8. Vascular Audits Mr.R Nelson, Dr S Renowden, Dr D Ainsley-Williams

    Subarachnoid haemorrhage: Ongoing database of patients since 1995. Writing of research papers and presentations of findings nationally and internationally

    Arterio-venous malformation: Currently setting up a database

    Outcomes following balloon occlusion of Carotid Artery

  9. Pituitary Surgery Mr D Sandeman, Mr R Nelson

    Baseline data for patients 1993-1998. Ongoing database of patients admitted since August1998

  10. Surgical outcomes following selective temporal lobectomy for temporal lobe epilepsy Mr David Sandeman

    n=60, with 5-15 new patients per year. Multi-professional audit: Neurosurgery, Neurology, Neurophysiology, Neuropsychiatry, Neuropsychology)

  11. Vagal Nerve Stimulators for Epilepsy Mr D Sandeman

    Outcome of vagus nerve stimulator implants.n=40, with 20 new patients per year. Multi-professional audit

  12. Outcome of transsphenoidal adenectomy for pituitary tumours Mr R Nelson, Mr D Sandeman, L Varian.

  13. Functional neurosurgery: Audit of the use of deep brain stimulating electrodes in the subthalamic nucleus in Parkinson’s Disease Mr S Gill

    Ongoing patient database, publication of research papers and presentations to national and international societies

  14. Functional neurosurgery: Audit of pallidotomy care pathway documentation K O’ Sullivan, S Gill

  15. Long term follow-up of choroid plexus coagulation versus ventriculo-peritoneal shunting Mr I Pople

    n=300 patients, May 00-Sept01

  16. Usefulness of Ommaya reservoirs in the assessment of patients following endoscopic third ventriculostomy Mr I Pople, Mr R Edwards

    n=95pts, Completion Feb01

  17. Shunt Infections in patients with Ventriculoperitoneal shunts Mr I Pople

    All shunt procedures are entered into the Department of Health-backed UK Shunt Registry. Our shunt infection rate for children under 5 years of age is one of the lowest in the country (c.1%). Our overall shunt infection rate has been reduced from 10% to 2.5% by implementation of a Shunt Protocol five years ago. This annual audit is benchmarked nationally.

  18. Endoscopic ventriculostomy in the treatment of intracranial tumours. Prof H Coakham, Mr I Pople, Y Clarke

    A recent audit of endoscopic procedures at Frenchay Hospital showed a success rate of 75% (international average: 65-75%) and a complication rate of 8% (infection and minor haemorrhage).

  19. Quality of life, disability and long-term outcome following anterior cervical decompression and fusion Mr P Grundy, Mr R Nelson

  20. Follow-up of outcome of C1/2 screws for rheumatoid arthritis Mr R Nelson

  21. Neurotheatres: 1) Audit of Infection rates 2) Audit of Skin Pressure care 3)Audit of Use of Mayfield Head clamp 4) Safe Specimen Transport to Neuropathology Lab Sr Wendy Soloman, Senior Nurse

    Annual re-audits in progress

  22. Audit Projects in the Neuroscience Nursing Services Sr Pearl Griffiths, Head of Nursing,

    Enteral feeding, Excretion of faeces, Venflons, Barrier nursing, Patient hand washing after toileting, Eye care, Care of ventricular/lumbar drains, Pain management, Pre-operative care, Care following lumbar puncture, Care following angiography, Patient nutrition, Oral hygiene, Male and female catheterisation, Care of catheters, Suction of tracheostomy, Documentation of patient admissions

NEUROSCIENCES LIBRARY

The library provides books and journals on neuroscience subjects - neurology, neurosurgery, neurophysiology, neuropharmacology, neuropathology, neuropsychiatry, neuropsychology.

Pre-1970 material is housed in Room 2, Ground Floor, Academic Centre, Frenchay Hospital. Post-1969 material is in the library on the 1st Floor of the Burden Centre, Frenchay Hospital. Current journals are kept in the Meeting Room where there is a photocopier.

  • Opening Hours Mon & Fri: 9.30 - 1 pm Tue, Wed & Thurs: 9.30 - 12.30, 1 - 4 pm

  • Library Staff

    Jane Sweetland, Neurosciences Librarian, Room 1.11, 1st. Floor, Burden Centre

    Ext. 2942, Fax 9186721, E-mail jane.sweetland@north-bristol.swest.nhs.uk

    Jack Britton, Honorary Librarian (Monday mornings)

  • Library & Information Services

    · Information and enquiry service to support patient care, teaching, continuing education and research

    · Inter-library loan facilities

    · Help with literature searches, reference checking, proof reading

    · Quiet study space - ideal for writing papers, exam. revision etc.

    · Access to University of Bristol network to authorised users

    · Library issues are discussed by the Neurosciences Library Management Board which has representatives from each specialty and is chaired by Professor Neil Scolding, Burden Professor of Clinical Neurosciences.

    · The Library collects details of papers published from within the Institute of Clinical Neurosciences. Please send reprints and/or details to Jane Sweetland, Neurosciences Library, The Burden Centre, Frenchay Hospital.

  • Stock Policy

    The Neurosciences Library is a reference-only library. Books and journals are not for loan, thereby giving equal access to everyone. Free photocopying is available. Requests for pre -1970 material held in the Academic Centre should be made via library staff.

  •  
    Comments or Technical Problems.
    Copyright copy 2001 Department of Neurosurgery, Frenchay Hospital, Frenchay, Bristol, UK     Phone +44 117 970 1212
    Email: nitin.patel@neurosurgery.uk.net


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